Description

4-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block primarily used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and functional materials due to its reactive iodine and ester functionalities. It is particularly sought after by the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures, including potential kinase inhibitors and organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Material Science Precursor: Serves as a building block for organic semiconductors, OLED materials, and conductive polymers.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for biochemical research.
• Academic & Industrial R&D: Essential for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	146137-85-1
Molecular Formula	C10H7IO2S
Molecular Weight	318.13 g/mol
Synonyms	Methyl 4-Iodobenzo[b]thiophene-2-carboxylate; 4-Iodobenzo[b]thiophene-2-carboxylic Acid Methyl Ester; Benzo[b]thiophene-2-carboxylic acid, 4-iodo-, methyl ester; Methyl 4-iodo-1-benzothiophene-2-carboxylate; 4-Iodo-1-benzothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.