Description

2-Thiophenesulfonamide, n-(1,1-Dimethylethyl)-5-(2-Methylpropyl)- is a specialized organic sulfonamide derivative featuring a thiophene core, designed for advanced chemical synthesis and research. This compound is valued for its role as a key intermediate or building block in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique sulfur-containing heterocycles into their molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the thiophene-sulfonamide moiety can impart specific biological activity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of advanced polymers, conductive materials, or organic semiconductors.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-Thiophenesulfonamide, n-(1,1-Dimethylethyl)-5-(2-Methylpropyl)-
CAS No.	146013-28-7
Molecular Formula	C12H21NO2S2
Molecular Weight	275.43 g/mol
Synonyms	N-tert-Butyl-5-isobutyl-2-thiophenesulfonamide; 5-Isobutyl-N-(tert-butyl)thiophene-2-sulfonamide; tert-Butyl(5-isobutyl-2-thienylsulfonyl)amine; 2-Thiophenesulfonamide, N-(1,1-dimethylethyl)-5-(2-methylpropyl)-; N-(tert-Butyl)-5-isobutylthiophene-2-sulfonamide; 146013-28-7; 5-(2-Methylpropyl)-N-(2-methyl-2-propanyl)-2-thiophenesulfonamide
EINECS	Contact for details

Quality Control

Our 2-Thiophenesulfonamide, n-(1,1-Dimethylethyl)-5-(2-Methylpropyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.