Description

Carbamic Acid, (2,5-Dioxo-1-Pyrrolidinyl)-, Methyl Ester (9Ci) is a high-purity chemical intermediate, also known as N-(Methoxycarbonyl)succinimide, valued for its role as a versatile building block in organic synthesis. Its primary importance lies in its function as a reagent for introducing the methoxycarbonyl (Moc) protecting group, which is crucial for the controlled synthesis of complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for peptide synthesis and other advanced manufacturing processes.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups in peptide and nucleotide chemistry.
• Agrochemical Synthesis: Used in the development and production of advanced crop protection agents and herbicides.
• Peptide Chemistry: Serves as a methoxycarbonylating agent for the temporary protection of amine functionalities during solid-phase and solution-phase peptide synthesis.
• Organic Synthesis Building Block: Employed in laboratory-scale and pilot-scale organic reactions to construct complex molecular architectures.
• Bioconjugation Reagent: Potential use in modifying biomolecules for research, diagnostics, and therapeutic applications.
• Polymer Chemistry: Can be utilized in the synthesis of functional polymers and materials science research.

Basic Information

Item	Detail
Product Name	Carbamic Acid, (2,5-Dioxo-1-Pyrrolidinyl)-, Methyl Ester (9Ci)
CAS No.	145967-17-5
Molecular Formula	C6H7NO5
Molecular Weight	173.12 g/mol
Synonyms	N-(Methoxycarbonyl)succinimide; Succinimidyl methyl carbonate; Methyl N-succinimidyl carbonate; NSC 405124; Methyl succinimidyl carbonate; Moc-OSu; N-(Methoxycarbonyloxy)succinimide; Carbonic acid, succinimidyl methyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (2,5-Dioxo-1-Pyrrolidinyl)-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.