Description

(1S,3R,4R,5S,6R)-5-(Benzyloxy)-3-((Benzyloxy)Methyl)-4-Methoxy-2,7-Dioxabicyclo[4.1.0]Heptane CAS NO 145852-85-3 is a high-purity, synthetically derived bicyclic ether compound with a complex stereochemistry. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in antiviral, antibacterial, and other therapeutic areas.
• Glycoscience Research: Used as a sophisticated precursor or model compound in the synthesis of complex carbohydrates, glycoconjugates, and glycomimetics.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce specific three-dimensional configurations into target molecules.
• Fine Chemical Production: Serves as a high-value building block for the manufacture of specialty chemicals, catalysts, and advanced materials requiring precise stereochemistry.
• Academic & Industrial R&D: Utilized in chemical biology and medicinal chemistry programs to explore structure-activity relationships and develop new synthetic methodologies.

Basic Information

Product Name	(1S,3R,4R,5S,6R)-5-(Benzyloxy)-3-((Benzyloxy)Methyl)-4-Methoxy-2,7-Dioxabicyclo[4.1.0]Heptane
CAS No.	145852-85-3
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	1,7-Anhydro-5-O-benzyl-3-C-(benzyloxymethyl)-4-deoxy-4-methoxy-D-glycero-D-gulo-heptitol; 5-O-Benzyl-3-C-(benzyloxymethyl)-4-deoxy-4-methoxy-1,7-anhydro-D-glycero-D-gulo-heptitol; Bicyclo[4.1.0]heptane, 5-(benzyloxy)-3-((benzyloxy)methyl)-4-methoxy-2,7-dioxa-, (1S,3R,4R,5S,6R)-; Benzyl-protected anhydro-heptitol derivative; Chiral bicyclic ether intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.