Description

(E)-Ethyl 2-Oxo-4-(Thiophen-2-Yl)But-3-Enoate is a high-purity, versatile α,β-unsaturated ester building block featuring a thiophene heterocycle. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical and advanced materials research. It is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific molecular frameworks into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating functional polymers and organic electronic materials like semiconductors.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds via reactions like Michael additions or cyclizations.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(E)-Ethyl 2-Oxo-4-(Thiophen-2-Yl)But-3-Enoate
CAS No.	145784-34-5
Molecular Formula	C10H10O3S
Molecular Weight	210.25 g/mol
Synonyms	Ethyl (2E)-2-oxo-4-(thiophen-2-yl)but-3-enoate; (E)-Ethyl 2-oxo-4-(2-thienyl)-3-butenoate; 2-Butenoic acid, 2-oxo-4-(2-thienyl)-, ethyl ester, (2E)-; Ethyl 2-oxo-4-(thiophen-2-yl)-3-butenoate; trans-Ethyl 2-oxo-4-(2-thienyl)-3-butenoate; 3-Butenoic acid, 2-oxo-4-(2-thienyl)-, ethyl ester; Ethyl (E)-2-oxo-4-(thiophen-2-yl)but-3-enoate
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 2-Oxo-4-(Thiophen-2-Yl)But-3-Enoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.