Description

4-Bromo-3-Nitrobenzenemethanol is a versatile aromatic building block featuring both bromo and nitro substituents, which serve as key handles for further synthetic elaboration. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex organic molecules. It is primarily utilized in pharmaceutical research, agrochemical synthesis, and as a precursor for advanced materials and dyes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring brominated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the nitro and bromo functional groups are critical for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex azo dyes and other colored compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries in discovery chemistry.

Basic Information

Product Name	4-Bromo-3-Nitrobenzenemethanol
CAS No.	145547-97-3
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	(4-Bromo-3-nitrophenyl)methanol; 4-Bromo-3-nitrobenzyl alcohol; 1-Bromo-2-nitro-4-(hydroxymethyl)benzene; Benzenemethanol, 4-bromo-3-nitro-; α-Hydroxy-4-bromo-3-nitrotoluene; 4-Bromo-3-nitro-benzenemethanol; 4-Bromo-3-nitrobenzylalcohol
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Nitrobenzenemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material and can support custom synthesis to meet specific purity or packaging requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.