Description

1-(2-Mercaptoethyl)Pyrrolidin-2-One is a specialized heterocyclic compound featuring both a pyrrolidone ring and a thiol functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly relevant for pharmaceutical chemists and material scientists working on novel drug candidates, polymer modifications, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring thiol or lactam functionalities.
• Polymer Chemistry: Used as a monomer or chain-transfer agent in the production of specialty polymers and for introducing sulfur-containing groups into polymer backbones.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands in coordination chemistry and catalysis.
• Bioconjugation: The thiol group enables its use in bioconjugation techniques for labeling proteins or other biomolecules.
• Chemical Research: A versatile reagent in organic synthesis for constructing complex heterocycles and exploring new reaction pathways.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	1-(2-Mercaptoethyl)Pyrrolidin-2-One
CAS No.	145526-47-2
Molecular Formula	C6H11NOS
Molecular Weight	145.22 g/mol
Synonyms	2-Pyrrolidinone, 1-(2-mercaptoethyl)-; 1-(2-Mercaptoethyl)-2-pyrrolidinone; N-(2-Mercaptoethyl)-2-pyrrolidinone; 2-(2-Oxopyrrolidin-1-yl)ethanethiol; 1-(2-Sulfanylethyl)pyrrolidin-2-one; Mercaptoethylpyrrolidone; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1-(2-Mercaptoethyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) providing specifications for assay, related substances, and physical properties is available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.