Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3As,7Ar)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a precise chiral scaffold for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Acts as a precursor or template in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Biochemical Research: Employed as a probe or ligand in the study of enzyme inhibition and receptor binding.
• Fine Chemical Production: Integrated into multi-step synthesis routes for high-value specialty chemicals.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3As,7Ar)-(9Ci)
CAS No.	145513-93-5
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S,3aS,7aR)-Octahydro-1H-indole-2-carboxylic acid; (2S,3aS,7aR)-Hexahydro-2H-indole-2-carboxylic acid; (2S,3aS,7aR)-Octahydroindole-2-carboxylic acid; cis-Octahydroindole-2-carboxylic acid (specified stereoisomer); L-Octahydroindole-2-carboxylic acid (stereospecific); OHIC; (2S,3aS,7aR)-2-Carboxyhexahydroindole
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3As,7Ar)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.