Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector where precise stereochemistry is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & Institutional Research: A valuable tool for methodological studies in organic chemistry, particularly in exploring new cyclization and functionalization reactions of indoline scaffolds.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-(9Ci)
CAS No.	145513-92-4
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(2R,3aS,7aR)-Octahydro-1H-indole-2-carboxylic acid; (2R,3aS,7aR)-Hexahydro-2H-indole-2-carboxylic acid; (2R,3aS,7aR)-Octahydroindole-2-carboxylic acid; cis-Octahydroindole-2-carboxylic acid (stereospecific); (2R,3aS,7aR)-Perhydroindole-2-carboxylic acid; (2R,3aS,7aR)-2-Carboxyhexahydroindole; Stereoisomer of Proline analog
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylicacid,Octahydro-,(2R,3As,7Ar)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profile is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.