Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3Ar,7Ar)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Serves as a sophisticated building block for constructing complex, enantiomerically pure molecules via various catalytic and stoichiometric methods.
• Medicinal Chemistry & Drug Discovery: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Agrochemical Research: Employed in the synthesis of novel, biologically active compounds for crop protection and pest management.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and heterocyclic chemistry.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3Ar,7Ar)-(9Ci)
CAS No.	145513-90-2
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(2S,3aR,7aR)-Octahydro-1H-indole-2-carboxylic acid; (2S,3aR,7aR)-Hexahydro-2H-indole-2-carboxylic acid; (2S,3aR,7aR)-Octahydroindole-2-carboxylic acid; (2S,3aR,7aR)-Perhydroindole-2-carboxylic acid; (2S,3aR,7aR)-2-Carboxyhexahydroindole; cis-(3aR,7aR)-Octahydro-1H-indole-2-carboxylic acid; (2S,3aR,7aR)-2-Carboxyoctahydroindole; L-Octahydroindole-2-carboxylic acid (stereospecific)
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylicacid,Octahydro-,(2S,3Ar,7Ar)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements for advanced research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.