Description

1-Boc-4-Iodomethyl-Piperidine is a versatile and highly valuable protected piperidine derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its primary value lies in the reactive iodomethyl group, which facilitates efficient alkylation and functionalization reactions, and the Boc-protected amine, which provides orthogonal deprotection capabilities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential treatments for neurological disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the piperidine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity tags for studying biological systems and protein interactions.
• Material Science Research: Utilized in the preparation of functionalized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functional group manipulation.

Basic Information

Product Name	1-Boc-4-Iodomethyl-Piperidine
CAS No.	145508-94-7
Molecular Formula	C11H20INO2
Molecular Weight	325.19 g/mol
Synonyms	1-tert-Butoxycarbonyl-4-iodomethylpiperidine; 4-(Iodomethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(iodomethyl)piperidine-1-carboxylate; N-Boc-4-iodomethylpiperidine; 1-Boc-4-(iodomethyl)piperidine; Piperidine, 4-(iodomethyl)-, 1-(1,1-dimethylethyl) ester; Boc-4-Iodomethylpiperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Iodomethyl-Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.