Description

2-Trimethylsilyl-1-propanol is a versatile organosilicon compound featuring both a reactive hydroxyl group and a silyl-protecting moiety. This bifunctional nature makes it a valuable intermediate and protecting group reagent in sophisticated organic synthesis. It is particularly essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors who require precise control over molecular architecture. The compound is supplied to meet the stringent quality demands of advanced R&D and production processes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where silicon-containing groups are required for drug delivery or activity modulation.
• Protecting Group Reagent: Used to selectively protect hydroxyl groups during multi-step synthetic sequences, offering stability under various reaction conditions and easy deprotection.
• Surface Modification Agent: Employed to functionalize silica, glass, or other inorganic surfaces, imparting hydrophobic properties or creating anchor points for further chemical grafting.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty silicones and hybrid organic-inorganic polymers with tailored properties.
• Liquid Crystal & Electronic Materials: Utilized in the synthesis of advanced materials for display technology and semiconductor applications due to its ability to influence molecular ordering and dielectric properties.
• Adhesive & Sealant Formulations: Functions as an adhesion promoter or a moisture scavenger in high-performance silicone-based adhesive and sealant systems.

Basic Information

Product Name	2-Trimethylsilyl-1-propanol
CAS No.	145428-83-7
Molecular Formula	C6H16OSi
Molecular Weight	132.28 g/mol
Synonyms	1-Propanol, 2-(trimethylsilyl)-; 2-(Trimethylsilyl)propan-1-ol; 2-(Trimethylsilyl)-1-propanol; 2-(Trimethylsilyl)ethanol, homologue; β-(Trimethylsilyl)ethanol; TMS-Propanol; (2-Hydroxypropyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilyl-1-propanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment. We are committed to meeting the specifications required for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.