Description

Eicosapentaenoic Acid-D5 CAS NO 145191-14-6 is a deuterium-labeled analog of the essential ω-3 fatty acid eicosapentaenoic acid (EPA). This stable isotope-labeled compound is a critical tool for quantitative mass spectrometry analysis, enabling precise tracking and measurement of EPA in complex biological matrices. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, nutraceutical, and clinical diagnostics sectors for method development, validation, and internal standardization.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a quantitative reference standard for the accurate measurement of endogenous EPA levels in pharmacokinetic and metabolomic studies.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of EPA and EPA-derived therapeutics.
• Clinical Research and Diagnostics: Enables precise quantification of EPA in human plasma, serum, and tissues for nutritional status assessment and biomarker discovery.
• Nutraceutical and Pharmaceutical Quality Control: Essential for the assay and impurity profiling of high-purity EPA active pharmaceutical ingredients (APIs) and finished dietary supplements.
• Biochemical Research: Facilitates the study of lipid metabolism, inflammation pathways, and the biochemical mechanisms of action of ω-3 fatty acids.

Basic Information

Item	Details
Product Name	Eicosapentaenoic Acid-D5
CAS No.	145191-14-6
Molecular Formula	C20H25D5O2
Molecular Weight	305.47 g/mol (approx.)
Synonyms	(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic-19,19,20,20,20-d5 acid; EPA-d5; all-cis-5,8,11,14,17-Eicosapentaenoic Acid-d5; Icosapentaenoic Acid-d5; Timnodonic Acid-d5; 20:5(n-3)-d5
EINECS	Contact for details

Quality Control

Our Eicosapentaenoic Acid-D5 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment, chemical purity (by HPLC), and identification. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance in your sensitive analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, solutions should be prepared in appropriate organic solvents and kept sealed under inert gas. Allow the sealed vial to warm to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solution
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 95%
Solvent (if supplied as solution)	Ethanol, Toluene, or as specified
Concentration (if supplied as solution)	1.0 mg/mL or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.