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[3-(Methylamino)Propyl]Triphenylphosphonium Bromide CAS NO 145126-87-0


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CAS No.:145126-87-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[3-(Methylamino)Propyl]Triphenylphosphonium Bromide is a versatile organophosphonium salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a Wittig reagent precursor and a phase-transfer catalyst, enabling critical carbon-carbon bond formation and facilitating reactions in biphasic systems. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for complex molecule construction.

Application

  • Wittig Reaction Reagent: Serves as a crucial precursor for generating ylides used in the synthesis of alkenes from carbonyl compounds, a fundamental transformation in medicinal chemistry.
  • Phase-Transfer Catalyst (PTC): Facilitates reactions between reactants in immiscible phases (e.g., aqueous and organic), improving yields and reaction rates in alkylation and other processes.
  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those containing alkene functionalities.
  • Agrochemical Synthesis: Employed in the production of herbicides, fungicides, and plant growth regulators that require specific alkene structures.
  • Material Science Research: Acts as a building block or catalyst in the development of novel polymers, liquid crystals, and organic electronic materials.
  • Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and exploring new synthetic pathways.

Basic Information

Product Name [3-(Methylamino)Propyl]Triphenylphosphonium Bromide
CAS No. 145126-87-0
Molecular Formula C22H25BrNP
Molecular Weight 414.32 g/mol
Synonyms (3-Methylaminopropyl)triphenylphosphonium bromide; N-Methyl-3-(triphenylphosphonio)propylamine bromide; 3-(Methylamino)-1-(triphenylphosphoranylidene)propan-1-ium bromide; MAPTPB; Triphenyl(3-(methylamino)propyl)phosphonium bromide; N-Methyl-3-(triphenylphosphoniumyl)propylamine bromide; (3-Methylaminopropyl)triphenylphosphonium bromide
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Quality Control

Our [3-(Methylamino)Propyl]Triphenylphosphonium Bromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect product performance. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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