Description

1H-Indole,2-Fluoro-1-Methyl-(9Ci) is a fluorinated indole derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in the strategic introduction of fluorine and methyl substituents on the indole scaffold, which can significantly alter the electronic, steric, and metabolic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research, where fluorinated indoles are prized for their enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the fluorine atom to improve lipophilicity and target binding.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other advanced electronic materials.
• Chemical Biology Probe Development: Employed in creating labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting synthetic methodology development and exploring new chemical spaces.

Basic Information

Product Name	1H-Indole,2-Fluoro-1-Methyl-(9Ci)
CAS No.	144951-50-8
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	2-Fluoro-1-methyl-1H-indole; 1-Methyl-2-fluoroindole; 2-Fluoro-1-methylindole; 1H-Indole, 2-fluoro-1-methyl-; 144951-50-8; 2-Fluoro-1-methyl-1H-indole (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Indole,2-Fluoro-1-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality systems support development from research quantities to commercial scale, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.