Description

3-(4-Bromo-2-Thienyl)Acrylic Acid is a high-value brominated thiophene derivative that serves as a versatile pharmaceutical intermediate and organic building block. Its unique structure, featuring both a reactive acrylic acid moiety and a brominated thiophene ring, makes it essential for constructing complex molecules in medicinal chemistry. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Building block for developing novel fungicides and herbicides with enhanced efficacy.
• Material Science: Monomer or precursor for conductive polymers and organic electronic materials due to the thiophene backbone.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport or emissive layer materials.
• Cross-Coupling Reactions: The bromine atom serves as a handle for palladium-catalyzed reactions (e.g., Suzuki, Heck) to create more complex biaryl structures.
• Ligand and Catalyst Development: Foundation for synthesizing novel chelating ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	3-(4-Bromo-2-Thienyl)Acrylic Acid
CAS No.	144558-44-1
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	trans-3-(4-Bromothiophen-2-yl)acrylic acid; (E)-3-(4-Bromothiophen-2-yl)acrylic Acid; 4-Bromo-2-thienylacrylic Acid; 3-(4-Bromo-2-thienyl)-2-propenoic acid; 2-Thiopheneacrylic acid, 4-bromo-; (E)-3-(4-Bromo-2-thienyl)acrylic Acid; 4-Bromo-2-thiopheneacrylic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-2-Thienyl)Acrylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.