Description

(2S, 3Ar,7As)-Benzyl Octahydro -1H-Indole-2-Carboxylate CAS NO 144540-71-6 is a high-purity, stereochemically defined indoline derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise molecular architecture for complex molecule construction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry and total synthesis projects.
• Fine Chemical Production: Acts as a building block for manufacturing specialized dyes, flavors, and fragrances that require a defined indoline core structure.

Basic Information

Product Name	(2S, 3Ar,7As)-Benzyl Octahydro -1H-Indole-2-Carboxylate
CAS No.	144540-71-6
Molecular Formula	C16H21NO2
Molecular Weight	259.34 g/mol
Synonyms	Benzyl (2S,3aR,7aS)-octahydro-1H-indole-2-carboxylate; (2S,3aR,7aS)-1,2,3,3a,4,5,6,7a-Octahydroindole-2-carboxylic acid benzyl ester; (2S,3aR,7aS)-2-Benzyloxycarbonyloctahydroindole; Octahydroindole-2-carboxylate benzyl ester; Chiral Indoline-2-carboxylate ester; BOC-Indoline derivative (related); Fmoc-Indoline building block (related); Stereoisomer of benzyl octahydroindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our (2S, 3Ar,7As)-Benzyl Octahydro -1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.