Description

1-(4-(Trifluoromethyl)Phenyl)But-3-En-1-Ol is a versatile chiral building block and intermediate in advanced organic synthesis. This compound is valued for its trifluoromethylphenyl group, which imparts unique electronic and steric properties critical for modulating the biological activity and physicochemical characteristics of target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Advanced Material Science: Building block for polymers and specialty chemicals requiring specific fluorine-containing motifs.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in academic and industrial research exploring new catalytic methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	1-(4-(Trifluoromethyl)Phenyl)But-3-En-1-Ol
CAS No.	144486-12-4
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	4-(Trifluoromethyl)benzeneethanol, α-Butenyl-4-(trifluoromethyl)benzenemethanol; 1-[4-(Trifluoromethyl)phenyl]-3-buten-1-ol; 3-Buten-1-ol, 1-[4-(trifluoromethyl)phenyl]-; (4-Trifluoromethylphenyl)but-3-en-1-ol; α-Vinyl-β-(4-trifluoromethylphenyl)ethanol
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethyl)Phenyl)But-3-En-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Typical)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.