Description

1-Benzenesulfonyl-1H-Indole-5-Carbonitrile is a high-value, multi-functional heterocyclic building block and synthetic intermediate. This compound matters for its role in facilitating complex molecular construction, particularly in the development of novel pharmacologically active agents. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating new chemical entities and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex indole-based molecules in academic and industrial R&D laboratories.
• Material Science: Investigated as a monomer or additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	1-Benzenesulfonyl-1H-Indole-5-Carbonitrile
CAS No.	144340-21-6
Molecular Formula	C15H10N2O2S
Molecular Weight	282.32 g/mol
Synonyms	5-Cyano-1-(phenylsulfonyl)indole; 1H-Indole-5-carbonitrile, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-1H-indole-5-carbonitrile; 1-Benzenesulfonyl-5-cyanoindole; 5-Cyano-1-(benzenesulfonyl)indole; 1-(Benzenesulfonyl)-5-cyanoindole; 1-(Phenylsulfonyl)indole-5-carbonitrile; Benzenesulfonyl-5-cyanoindole
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by analytical techniques including HPLC, NMR, and mass spectrometry. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.