Description

3H-Indol-3-One, 1-Acetyl-2-[(4-Bromophenyl)Chloromethyl]-2-Chloro-1,2-Dihydro- is a specialized halogenated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring bromo and chloro substituents, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel heterocyclic compounds for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging its halogenated indole core.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce functionalized indole motifs into larger molecular frameworks.
• Material Science Research: Investigated as a monomer or precursor for the creation of specialized organic electronic materials and dyes.
• Academic & Contract Research: Serves as a standard or experimental reagent in university laboratories and CROs (Contract Research Organizations) for methodological studies.

Basic Information

Product Name	3H-Indol-3-One, 1-Acetyl-2-[(4-Bromophenyl)Chloromethyl]-2-Chloro-1,2-Dihydro-
CAS No.	144294-78-0
Molecular Formula	C17H12BrCl2NO
Molecular Weight	397.10 g/mol
Synonyms	1-Acetyl-2-[(4-bromophenyl)chloromethyl]-2-chloro-1,2-dihydro-3H-indol-3-one; 2-Chloro-1-acetyl-2-[(4-bromophenyl)chloromethyl]-1,2-dihydro-3H-indol-3-one; 1,2-Dihydro-3H-indol-3-one, 1-acetyl-2-[(4-bromophenyl)chloromethyl]-2-chloro-; 144294-78-0; (4-Bromophenyl)chloromethyl-substituted indolone derivative
EINECS	Contact for details

Quality Control

Our production of 3H-Indol-3-One, 1-Acetyl-2-[(4-Bromophenyl)Chloromethyl]-2-Chloro-1,2-Dihydro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support development projects requiring material that meets exacting research-grade or GMP-starting material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.