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tert-Butyl-Dimethyl-[7A-Methyl-1-(1,4,5-Trimethyl-Hex-2-Enyl)-Octahydro-Inden-4-Yloxy]-Silane CAS NO 144177-03-7


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CAS No.:144177-03-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl-Dimethyl-[7A-Methyl-1-(1,4,5-Trimethyl-Hex-2-Enyl)-Octahydro-Inden-4-Yloxy]-Silane is a specialized organosilicon compound, a key protected intermediate in advanced organic synthesis. Its primary value lies in providing a robust tert-butyldimethylsilyl (TBDMS) protecting group for hydroxyl functionalities, offering superior stability under a wide range of reaction conditions compared to other silyl ethers. This makes it an essential reagent for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the multi-step synthesis of complex molecules like steroids, terpenoids, and active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: Critical for the synthesis of complex drug molecules, especially in steroid and terpenoid-based therapeutic agents.
  • Fine Chemical Synthesis: Used as a key protecting group reagent in multi-step organic synthesis to selectively mask hydroxyl groups.
  • Academic & Industrial Research: A valuable tool for chemists developing new synthetic methodologies and exploring novel chemical entities.
  • Agrochemical Development: Potential intermediate in the synthesis of advanced, high-performance crop protection agents.
  • Fragrance & Flavor Chemistry: Employed in the controlled synthesis of specific terpenoid components for high-value aroma chemicals.
  • Material Science Precursor: Can serve as a precursor or modifying agent in the development of specialized silicone-based polymers.

Basic Information

Item Details
Product Name tert-Butyl-Dimethyl-[7A-Methyl-1-(1,4,5-Trimethyl-Hex-2-Enyl)-Octahydro-Inden-4-Yloxy]-Silane
CAS No. 144177-03-7
Molecular Formula C24H46OSi
Molecular Weight 378.72 g/mol
Synonyms (3β,5α)-3-[(tert-Butyldimethylsilyl)oxy]-lanost-8-en-24-ol; Lanosta-8-en-3-ol, 24-hydroxy-, 3-(1,1-dimethylethyl)dimethylsilyl ether, (3β,5α,24R)-; 24-Hydroxylanost-8-en-3-yl tert-butyldimethylsilyl ether; TBDMS ether of 24-hydroxylanosterol; 24-Hydroxylanosterol TBDMS ether; (24R)-24-Hydroxylanost-8-en-3β-yl tert-butyldimethylsilyl ether; Lanosterol derivative TBDMS ether
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Quality Control

Our tert-Butyl-Dimethyl-[7A-Methyl-1-(1,4,5-Trimethyl-Hex-2-Enyl)-Octahydro-Inden-4-Yloxy]-Silane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Assay ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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