Description

Silymarin, 80% CAS NO 144160-53-2 is a standardized extract derived from the seeds of the milk thistle plant (*Silybum marianum*), primarily composed of flavonolignans including silybin, isosilybin, silychristin, and silydianin. This potent botanical compound is valued for its hepatoprotective and antioxidant properties, making it a critical ingredient for supporting liver health and function. It is essential for manufacturers in the pharmaceutical, nutraceutical, and dietary supplement industries seeking a reliable, high-purity active ingredient.

Application

• Pharmaceutical Formulations: Core active ingredient in prescription and over-the-counter (OTC) hepatoprotective medicines for treating liver conditions such as cirrhosis, hepatitis, and fatty liver disease.
• Dietary Supplements & Nutraceuticals: Key component in capsules, tablets, and liquid extracts marketed for liver detoxification, support, and overall antioxidant health.
• Functional Food & Beverages: Incorporated into health-focused food products and drinks designed to promote wellness and liver function.
• Cosmeceuticals: Used in topical skincare formulations for its anti-inflammatory and antioxidant benefits, helping to protect skin from environmental damage.
• Veterinary Pharmaceuticals: Applied in animal health products to support liver function in pets and livestock.
• Research & Development: Serves as a standard or investigational material in biochemical and pharmacological studies related to liver metabolism and cytoprotection.

Basic Information

Product Name	Silymarin, 80%
CAS No.	144160-53-2
Molecular Formula	Mixture (C25H22O10 for Silybin)
Molecular Weight	482.44 g/mol (for Silybin)
Synonyms	Milk Thistle Extract; Silybum marianum Extract; Legalon; Silibinin; Flavonolignans from Milk Thistle; Silymarin Flavonoids; Hepatoprotective Flavonolignan Complex; Carduus marianus Extract
EINECS	Contact for details

Quality Control

Our Silymarin 80% is produced under strict quality management systems. Each batch is tested to confirm identity, potency, and purity, ensuring it meets stringent specifications for heavy metals, residual solvents, and microbiological contamination. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Complies
Assay (Silymarin Flavonolignans)	NLT 80.0%
Silybin A+B	NLT 30.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
E. Coli	Negative
Salmonella	Negative

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.