Description

Boc-4-Aminobenzylalcohol CAS NO 144072-29-7 is a protected amino alcohol derivative, specifically featuring a tert-butoxycarbonyl (Boc) group on the amine functionality of 4-aminobenzyl alcohol. This compound is a crucial building block in organic synthesis, particularly in peptide and pharmaceutical chemistry, where it serves as a versatile intermediate for the introduction of the 4-aminobenzyl moiety. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the 4-aminobenzyl alcohol scaffold, often for linker or spacer applications.
• Protecting Group Chemistry: The Boc group provides a base-labile protecting strategy for amines, enabling selective deprotection in multi-step synthetic sequences.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands or organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Acts as a monomer or functionalization agent for synthesizing specialty polymers, dendrimers, or functionalized surfaces.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	Boc-4-Aminobenzylalcohol
CAS No.	144072-29-7
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]benzyl alcohol; 1-[(tert-Butoxycarbonyl)amino]-4-(hydroxymethyl)benzene; N-Boc-4-aminobenzyl alcohol; tert-Butyl (4-(hydroxymethyl)phenyl)carbamate; N-(tert-Butoxycarbonyl)-4-aminobenzyl alcohol; Boc-4-Aminobenzyl Alcohol; 4-(Boc-amino)benzyl alcohol; Boc-Abz-OH (Note: Abz = 4-aminobenzyl alcohol)
EINECS	Contact for details

Quality Control

Our Boc-4-Aminobenzylalcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP guidelines for production where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.