Description

2-(4-Fluorophenyl)-4-Methyl-5-Thiazolecarboxylicacid is a high-purity, fluorinated thiazole derivative serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its precise molecular architecture, enabling the construction of complex pharmacophores and functional materials. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and fluorophenyl motifs.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-(4-Fluorophenyl)-4-Methyl-5-Thiazolecarboxylicacid
CAS No.	144060-99-1
Molecular Formula	C11H8FNO2S
Molecular Weight	237.25 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-(4-fluorophenyl)-4-methyl-; 2-(p-Fluorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid; 4-Methyl-2-(4-fluorophenyl)thiazole-5-carboxylic acid; 2-(4-Fluorophenyl)-4-methylthiazole-5-carboxylic acid; 144060-99-1; AKOS BRN 0978; ZINC000257019509; SCHEMBL11826979
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluorophenyl)-4-Methyl-5-Thiazolecarboxylicacid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.