Description

Bicyclo[2.2.1]Heptan-2-One, 1-Methyl-3-(Trifluoroacetyl)- (9Ci) CAS NO 143874-05-9 is a specialized fluorinated bicyclic ketone that serves as a high-value synthetic intermediate. Its unique structure, featuring a norbornane skeleton and a trifluoroacetyl group, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for R&D and production in the pharmaceutical and advanced materials sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with unique thermal or optical properties.
• Organic Synthesis & Catalysis: A versatile reagent for constructing complex bicyclic frameworks in academic and industrial research laboratories.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing novel aroma chemicals with complex, woody, or camphoraceous notes.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-2-One, 1-Methyl-3-(Trifluoroacetyl)- (9Ci)
CAS No.	143874-05-9
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	1-Methyl-3-(trifluoroacetyl)bicyclo[2.2.1]heptan-2-one; 3-(Trifluoroacetyl)-1-methyl-2-norbornanone; 1-Methyl-3-trifluoroacetyl-2-norbornanone; 2-Norbornanone, 1-methyl-3-(trifluoroacetyl)-; Bicyclo[2.2.1]heptan-2-one, 1-methyl-3-(trifluoroacetyl)-; 143874-05-9 (CAS); 1-Methyl-3-(2,2,2-trifluoroacetyl)bicyclo[2.2.1]heptan-2-one
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptan-2-One, 1-Methyl-3-(Trifluoroacetyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require desiccant or an inert atmosphere for long-term storage. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.