Description

(3-Bromomethylphenyl)Boronic Acid Neopentyl Glycol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining a key reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific aromatic coupling steps.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	(3-Bromomethylphenyl)Boronic Acid Neopentyl Glycol Ester
CAS No.	143805-78-1
Molecular Formula	C₁₄H₂₀BBrO₂
Molecular Weight	311.02 g/mol
Synonyms	[3-(Bromomethyl)phenyl]boronic acid neopentyl glycol ester; (3-Bromobenzyl)boronic acid pinacol ester (common misnomer); Benzene, 1-(bromomethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-[3-(Bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromomethylbenzeneboronic acid neopentyl glycol cyclic ester; Boronic acid, B-[3-(bromomethyl)phenyl]-, 2,2-dimethyl-1,3-propanediyl ester
EINECS	Contact for details

Quality Control

Our (3-Bromomethylphenyl)Boronic Acid Neopentyl Glycol Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.