Description

1H,3H-Pyrrolo[1,2-C][1,3,2]Oxazaborole, Tetrahydro-1-Ethyl-3,3-Diphenyl-, (S)- is a high-value, chiral organoboron compound, specifically a boronate ester, with the CAS number 143800-16-2. Its primary commercial value lies in its role as a key chiral ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, stereochemically defined intermediates.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor for enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediates: In the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Synthesis: For the production of chiral herbicides, fungicides, and pesticides.
• Material Science Research: As a building block for novel chiral polymers or organic electronic materials.
• Academic & Industrial R&D: For method development and exploration of new asymmetric transformations in organic chemistry.
• Fine Chemical Production: In the manufacture of specialty flavors, fragrances, and other high-value chiral compounds.

Basic Information

Product Name	1H,3H-Pyrrolo[1,2-C][1,3,2]Oxazaborole, Tetrahydro-1-Ethyl-3,3-Diphenyl-, (S)-
CAS No.	143800-16-2
Molecular Formula	C20H24BNO
Molecular Weight	305.22 g/mol
Synonyms	(S)-1-Ethyl-3,3-diphenyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; (S)-1-Ethyl-3,3-diphenyl-1,3,3a,4,5,6-hexahydro-2H-pyrrolo[1,2-c][1,3,2]oxazaborole; (S)-Ethyl-Diphenyl-Boronate-Pyrrolidine Complex; Chiral Oxazaborolidine Catalyst; (S)-CBS Catalyst Derivative; (S)-Diphenylprolinol Boronate Ester; Asymmetric Boron Reagent
EINECS	Contact for details

Quality Control

Our production of this chiral organoboron compound adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through comprehensive analytical methods including HPLC, chiral HPLC, 1H/13C/11B NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, chiral purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.