Description

4-Bromo-1,1-dioxo-tetrahydrothiophen-3-one is a high-purity brominated sulfone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a reactive handle for constructing complex molecules, particularly in the development of pharmaceuticals and specialty chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise building blocks for active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those containing functionalized heterocyclic cores.
• Agrochemical Synthesis: Used in the development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a precursor for specialty polymers and functional materials with specific electronic or structural properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex molecular architectures in R&D laboratories.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Bromo-1,1-dioxo-tetrahydrothiophen-3-one
CAS No.	143654-18-6
Molecular Formula	C4H5BrO3S
Molecular Weight	213.05 g/mol
Synonyms	4-Bromo-1,1-dioxotetrahydro-3-thiophenone; 4-Bromo-3-oxotetrahydrothiophene 1,1-dioxide; 3-Thiophenone, 4-bromotetrahydro-, 1,1-dioxide; Tetrahydro-4-bromo-3-thiophenone 1,1-dioxide; 4-Bromosulfolane-3-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,1-dioxo-tetrahydrothiophen-3-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.