Description

8-Chloro-2,3-dihydroimidazo[1,2-a]pyrazine hydrochloride is a high-purity pharmaceutical intermediate and heterocyclic building block of significant synthetic value. Its core value proposition lies in enabling the efficient synthesis of complex molecules, particularly in medicinal chemistry research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the imidazopyrazine core.
• Agrochemical Synthesis: Serves as a precursor for developing new active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: A versatile synthon for constructing complex heterocyclic frameworks in custom synthesis and contract manufacturing.

Basic Information

Product Name	8-Chloro-2,3-dihydroimidazo[1,2-a]pyrazine hydrochloride
CAS No.	143592-06-7
Molecular Formula	C6H7Cl2N3
Molecular Weight	192.05 g/mol
Synonyms	8-Chloro-2,3-dihydroimidazo[1,2-a]pyrazine HCl; 8-Chloro-2,3-dihydro-1H-imidazo[1,2-a]pyrazine hydrochloride; Imidazo[1,2-a]pyrazine, 8-chloro-2,3-dihydro-, hydrochloride (1:1); 143592-06-7; 8-Chloro-1H-imidazo[1,2-a]pyrazine hydrochloride; 8-Chloro-2,3-dihydroimidazo[1,2-a]pyrazin-2-ium chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2,3-dihydroimidazo[1,2-a]pyrazine hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.