Description

1-Ethyl-2,3-Dihydro-1H-Indol-6-Amine is a versatile indoline derivative, a key heterocyclic amine building block prized for its role in advanced organic synthesis. Its structural motif is critical for constructing complex molecules with specific biological and chemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, serving as a foundational intermediate for active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators due to its bioactive indoline core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transporting or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and functional colorants.
• Academic and R&D Laboratories: Used extensively in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Ethyl-2,3-Dihydro-1H-Indol-6-Amine
CAS No.	143543-67-3
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	6-Amino-1-ethyl-2,3-dihydro-1H-indole; 1-Ethyl-1,2,3,4-tetrahydro-6-quinolinamine; 1-Ethyl-2,3-dihydro-1H-indol-6-ylamine; 1-Ethyl-6-aminoindoline; 6-Amino-1-ethylindoline; 143543-67-3; 1H-Indol-6-amine, 1-ethyl-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 1-Ethyl-2,3-Dihydro-1H-Indol-6-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.