Description

1-[4-(Chloromethyl)Phenyl]-1H-1,2,4-Triazole is a versatile and high-value heterocyclic building block, primarily used as a key intermediate in the synthesis of more complex molecules. Its core value lies in the reactive chloromethyl group attached to the phenyl ring, which allows for efficient functionalization and coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators, leveraging the bioactivity of the 1,2,4-triazole moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with enhanced thermal or chemical stability.
• Organic Synthesis & Catalysis: Acts as a ligand precursor in organometallic chemistry and catalysis, facilitating various coupling and transformation reactions.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-[4-(Chloromethyl)Phenyl]-1H-1,2,4-Triazole
CAS No.	143426-53-3
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	4-(Chloromethyl)phenyl-1,2,4-triazole; 1-(4-Chloromethylphenyl)-1H-1,2,4-triazole; 1H-1,2,4-Triazole, 1-[4-(chloromethyl)phenyl]-; (4-(1H-1,2,4-Triazol-1-yl)phenyl)methyl chloride; 1-(4-Chlorobenzyl)-1H-1,2,4-triazole; 4-(1H-1,2,4-Triazol-1-yl)benzyl chloride
EINECS	Contact for details

Quality Control

Our 1-[4-(Chloromethyl)Phenyl]-1H-1,2,4-Triazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.