Description

(R)-1-Amino-3-(9H-Carbazol-4-Yloxy)-2-Propanol is a chiral amino alcohol derivative of carbazole, serving as a high-value pharmaceutical intermediate and chiral building block. This compound matters for its role in the stereoselective synthesis of active pharmaceutical ingredients (APIs), where the (R)-configuration is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel therapeutics, particularly β-adrenergic blocking agents and other receptor-targeted molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers and other cardiovascular drugs.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereogenic centers into complex organic molecules.
• Chemical Research & Development: Serves as a standard or starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in the scale-up and optimization of API manufacturing routes.
• Ligand Synthesis: Potential precursor for chiral ligands used in catalysis.

Basic Information

Product Name	(R)-1-Amino-3-(9H-Carbazol-4-Yloxy)-2-Propanol
CAS No.	143412-41-3
Molecular Formula	C19H20N2O2
Molecular Weight	308.38 g/mol
Synonyms	(R)-1-Amino-3-(carbazol-4-yloxy)-2-propanol; (R)-4-(2-Hydroxy-3-aminopropoxy)carbazole; (R)-Carvedilol Intermediate; (R)-1-Amino-3-(9H-Carbazol-4-Yloxy)Propan-2-ol; (R)-4-(2-Hydroxy-3-aminopropoxy)-9H-carbazole; (R)-Amino Carbazole Propanol Derivative; (R)-ACP
EINECS	Contact for details

Quality Control

Our (R)-1-Amino-3-(9H-Carbazol-4-Yloxy)-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.