Description

(5-Methylbenzofuran-2-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically through the Suzuki-Miyaura cross-coupling reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing benzofuran scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides via palladium-catalyzed coupling reactions.
• Material Science: Serves as a monomer or precursor for constructing organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Chemical Synthesis: Enables the efficient introduction of the 5-methylbenzofuran-2-yl moiety into more complex molecules in medicinal and process chemistry.
• Ligand & Catalyst Development: Utilized in the preparation of novel bidentate ligands for transition metal catalysis.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in laboratory-scale and pilot-scale operations.

Basic Information

Product Name	(5-Methylbenzofuran-2-Yl)Boronic Acid
CAS No.	143381-72-0
Molecular Formula	C9H9BO3
Molecular Weight	176.0 g/mol
Synonyms	5-Methyl-2-benzofuranboronic Acid; (5-Methyl-2-benzofuranyl)boronic Acid; 2-(5-Methylbenzofuran-2-yl)boronic Acid; B-(5-Methyl-2-benzofuranyl)boronic Acid; 5-Methylbenzofuran-2-boronic Acid; 5-Methyl-2-furanboronic Acid; 143381-72-0; (5-Methyl-benzo[b]furan-2-yl)boronic acid
EINECS	Contact for details

Quality Control

Our (5-Methylbenzofuran-2-Yl)Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for critical cross-coupling applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.