Description

(R)-5-Bromo-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole CAS NO 143322-57-0 is a high-purity chiral indole derivative, a crucial advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its defined stereochemistry and functionalized indole core, which are essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands or organocatalysts for synthetic applications.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical manufacturing.
• Chemical Biology Probes: Used in the development of molecular probes to study biological pathways and protein function.

Basic Information

Product Name	(R)-5-Bromo-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole
CAS No.	143322-57-0
Molecular Formula	C₁₄H₁₇BrN₂
Molecular Weight	293.20 g/mol
Synonyms	(R)-5-Bromo-3-((1-methyl-2-pyrrolidinyl)methyl)-1H-indole; (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole; 1H-Indole, 5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-, (2R)-; (R)-5-Bromo-3-(1-methylpyrrolidin-2-ylmethyl)indole; (R)-5-Bromo-3-[(1-methylpyrrolidin-2-yl)methyl]indole; (R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)indole; (R)-5-Bromo-3-(1-methylpyrrolidin-2-ylmethyl)-1H-indole; (R)-5-Bromo-3-((1-methyl-2-pyrrolidinyl)methyl)indole
EINECS	Contact for details

Quality Control

Our (R)-5-Bromo-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot undergoes rigorous analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.