Description

(R)-5-Bromo-3-[(1-Methyl-2-Pyrrolidinyl)Methyl]-1H-Indole is a high-purity chiral indole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its specific stereochemistry and functional groups, which make it an essential building block for creating complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents, particularly in neurological and psychiatric research.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for compounds with indole-based scaffolds.
• Asymmetric Synthesis: Serves as a sophisticated building block for constructing complex molecules with defined stereocenters.
• Biochemical Tool Compound: Potential use in developing receptor ligands for pharmacological and neurological research applications.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high regio- and stereoselectivity.

Basic Information

Product Name	(R)-5-Bromo-3-[(1-Methyl-2-Pyrrolidinyl)Methyl]-1H-Indole
CAS No.	143322-56-9
Molecular Formula	C15H19BrN2
Molecular Weight	307.23 g/mol
Synonyms	(R)-5-Bromo-3-[(1-Methylpyrrolidin-2-yl)methyl]-1H-indole; (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole; 1H-Indole, 5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-, (R)-; (R)-5-Bromo-3-(1-methylpyrrolidin-2-ylmethyl)indole; (R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]indole; (R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)indole; (R)-5-Bromo-3-(1-methylpyrrolidin-2-ylmethyl)-1H-indole
EINECS	Contact for details

Quality Control

Our (R)-5-Bromo-3-[(1-Methyl-2-Pyrrolidinyl)Methyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.