Description

(R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole CAS NO 143322-55-8 is a chiral indole derivative of significant interest in advanced organic synthesis. This compound serves as a key chiral building block and pharmacological intermediate for the development of active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly those targeting neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those with chiral centers.
• Neurological Research: Used in the development of compounds targeting serotonin and other neurotransmitter receptors.
• Asymmetric Synthesis: Employed as a chiral ligand or scaffold in catalytic reactions to induce stereoselectivity.
• Medicinal Chemistry R&D: Serves as a core structure for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole
CAS No.	143322-55-8
Molecular Formula	C15H20N2
Molecular Weight	228.34 g/mol
Synonyms	(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-indole; (R)-3-(1-Methylpyrrolidin-2-ylmethyl)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)indole; (R)-3-(1-Methyl-2-pyrrolidinylmethyl)indole; (R)-3-(N-Methylpyrrolidin-2-ylmethyl)indole; (R)-Indole-3-ylmethyl-N-methylpyrrolidine; (R)-1-Methyl-2-(1H-indol-3-ylmethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indole is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.