Description

(R)-Benzyl 2-((5-Bromo-1H-Indol-3-Yl)Methyl)Pyrrolidine-1-Carboxylate is a high-value chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Neurological Research: Used in the development of compounds targeting serotonin and other neurotransmitter receptors due to its indole-pyrrolidine scaffold.
• Oncology Research: Serves as a precursor in the synthesis of molecules being investigated for anti-cancer properties.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Chemical Biology: Utilized as a probe or tool compound in studying biological mechanisms and protein interactions.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(R)-Benzyl 2-((5-Bromo-1H-Indol-3-Yl)Methyl)Pyrrolidine-1-Carboxylate
CAS No.	143322-46-7
Molecular Formula	C22H23BrN2O2
Molecular Weight	427.34 g/mol
Synonyms	(R)-Benzyl 2-((5-bromo-1H-indol-3-yl)methyl)pyrrolidine-1-carboxylate; 1-[(5-Bromo-1H-indol-3-yl)methyl]-2-pyrrolidinecarboxylic Acid Phenylmethyl Ester, (2R)-; (R)-1-((5-Bromo-1H-indol-3-yl)methyl)pyrrolidine-2-carboxylic Acid Benzyl Ester; (R)-Cbz-5-Bromo-tryptophan Methyl Ester Cyclized Derivative; (R)-Benzyl 5-Bromotryptophan Prolinol Derivative; (2R)-1-[(5-Bromo-1H-indol-3-yl)methyl]pyrrolidine-2-carboxylic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 2-((5-Bromo-1H-Indol-3-Yl)Methyl)Pyrrolidine-1-Carboxylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Enantiomeric Purity (Chiral HPLC)	≥98.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.