Description

7-Bromo-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex heterocyclic molecules, enabling efficient and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Organic Synthesis: Versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other functional group manipulations due to the reactive bromine substituent.
• Material Science: Potential monomer or intermediate for creating specialized polymers and organic electronic materials with unique optoelectronic properties.
• Chemical Biology: Useful for synthesizing molecular probes and labeled compounds for studying biological pathways and protein interactions.

Basic Information

Product Name	7-Bromo-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	143262-17-3
Molecular Formula	C13H16BrNO2
Molecular Weight	298.18 g/mol
Synonyms	1-Boc-7-bromo-2,3-dihydroindole; 7-Bromo-1-N-Boc-2,3-dihydroindole; tert-Butyl 7-bromo-2,3-dihydro-1H-indole-1-carboxylate; 7-Bromoindoline-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-7-bromo-2,3-dihydroindole; 7-Bromo-2,3-dihydro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 143262-17-3; 7-Bromo-1-N-Boc-indoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.