Description

Benzenethiol, 2-Amino-3,6-Difluoro- (9Ci) is a specialized aromatic thiol derivative featuring amino and fluoro substituents, making it a valuable multi-functional building block for advanced synthesis. Its unique structure offers significant potential for creating complex molecules with tailored electronic and steric properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in drug discovery, ligand synthesis, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used to create sophisticated ligands for transition metal catalysis in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and bioconjugation reagents due to the reactive thiol and amino groups.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	Benzenethiol, 2-Amino-3,6-Difluoro- (9Ci)
CAS No.	143163-91-1
Molecular Formula	C6H5F2NS
Molecular Weight	161.17 g/mol
Synonyms	2-Amino-3,6-difluorobenzenethiol; 3,6-Difluoro-2-aminobenzenethiol; 2-Amino-3,6-difluorothiophenol; 2-Amino-3,6-difluorophenyl mercaptan; 1,2-Difluoro-4-mercapto-3-aminobenzene; 143163-91-1 (CAS); 2-Amino-3,6-difluorobenzene-1-thiol
EINECS	Contact for details

Quality Control

Our production of Benzenethiol, 2-Amino-3,6-Difluoro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.