Description

(E)-2-(Benzylideneamino)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carbonitrile is a high-value, heterocyclic organic compound featuring a benzothiophene core with strategically positioned nitrile and imine functional groups. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new herbicides and fungicides, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: Employed in complex organic synthesis for constructing fused-ring systems and introducing specific functional groups.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Item	Details
Product Name	(E)-2-(Benzylideneamino)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carbonitrile
CAS No.	142994-71-6
Molecular Formula	C₁₆H₁₄N₂S
Molecular Weight	266.36 g/mol
Synonyms	2-[(E)-Benzylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile; (E)-2-(Benzylideneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile; 4,5,6,7-Tetrahydro-2-[(phenylmethylene)amino]benzo[b]thiophene-3-carbonitrile; 2-Benzylideneamino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile; 142994-71-6; Benzothiophene-3-carbonitrile derivative
EINECS	Contact for details

Quality Control

We supply this compound in high-purity grades suitable for research and development. All batches undergo rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality parameters. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.