Description

1-(Benzo(B)Thiophen-5-Yl)-2-(1-(Nicotinoylamino)Ethoxy)Ethanol Hydrochloride is a high-purity, non-racemic synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule is valued for its complex heterocyclic structure, which serves as a critical intermediate or active scaffold in the design of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for targeted synthesis programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or probe molecule in pharmacological and enzymatic studies.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Custom Synthesis: Starting material for the preparation of more complex, proprietary derivatives for specialized research applications.

Basic Information

Product Name	1-(Benzo(B)Thiophen-5-Yl)-2-(1-(Nicotinoylamino)Ethoxy)Ethanol Hydrochloride
CAS No.	142934-83-6
Molecular Formula	C18H19N3O3S • HCl
Molecular Weight	393.88 g/mol (Free base: 357.43 g/mol)
Synonyms	1-(Benzo[b]thiophen-5-yl)-2-[1-(nicotinoylamino)ethoxy]ethanol hydrochloride; 1-(5-Benzothienyl)-2-[1-[(3-pyridinylcarbonyl)amino]ethoxy]ethanol hydrochloride; (R/S)-1-(Benzo[b]thiophen-5-yl)-2-[(1-(nicotinamido)ethoxy]ethanol HCl; Nicotinamide, N-[1-[[2-hydroxy-2-(5-benzothienyl)ethoxy]ethyl]-, hydrochloride; Research Code Compound (various); Pharmaceutical Intermediate 142934-83-6
EINECS	Contact for details

Quality Control

Our 1-(Benzo(B)Thiophen-5-Yl)-2-(1-(Nicotinoylamino)Ethoxy)Ethanol Hydrochloride is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is assured through rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.