Description

Silybin (A And B)(P) is a standardized, high-purity mixture of the principal bioactive flavonolignans, Silybin A and Silybin B, derived from the milk thistle plant (*Silybum marianum*). This compound is critically valued for its potent antioxidant and hepatoprotective properties, making it a key active pharmaceutical ingredient (API) and nutraceutical component. It is primarily utilized by manufacturers in the pharmaceutical, dietary supplement, and cosmeceutical industries for developing liver support formulations, detox products, and advanced skincare solutions.

Application

• Pharmaceutical Active Ingredient (API): Core component in prescription and OTC medications for liver conditions, including toxin-induced liver damage, alcoholic liver disease, and hepatitis.
• Dietary Supplements & Nutraceuticals: Key ingredient in capsules, tablets, and liquid extracts marketed for liver detoxification, support, and overall cellular health.
• Cosmeceutical Formulations: Incorporated into anti-aging serums, creams, and lotions for its antioxidant properties that protect skin from environmental stressors and UV-induced damage.
• Veterinary Medicine: Used in veterinary supplements and treatments for hepatoprotective support in companion animals and livestock.
• Research & Development: Serves as a reference standard and biochemical tool in pharmacological, toxicological, and metabolic studies.
• Functional Food & Beverage Fortification: Potential use in enriching health-focused food and drink products with targeted wellness benefits.

Basic Information

Product Name	Silybin (A And B)(P)
CAS No.	142797-34-0
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	Silibinin; Silymarin I; Silybin; Silybinin; Silybin A and B Mixture; (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one; Milk Thistle Extract (Standardized); Flavonolignan Complex
EINECS	Contact for details

Quality Control

Our Silybin (A And B)(P) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and microbiological parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Complies
Identification (IR)	Complies
Assay (HPLC)	≥ 98.0% (Total Silybin A & B)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C
Total Aerobic Microbial Count	≤ 1000 cfu/g
Total Yeast & Mold Count	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.