Description

4-(3,4-Dihydro-6,7-Dimethoxy-2(1H)-Isoquinolinyl)-n-[2-(3,4-Dimethoxyphenyl)Ethyl]-6,7-Dimethoxy-2-Quinazolinamine Monohydrochloride CAS NO 142715-48-8 is a high-purity, complex heterocyclic compound belonging to the quinazolinamine class. This compound is of significant interest for its potential as a key pharmaceutical intermediate or research chemical in the development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a reference standard or starting material in structure-activity relationship (SAR) studies to optimize biological activity.
• Biochemical Research: Employed in in vitro assays to investigate interactions with specific enzymes or receptors, aiding in target validation.
• Academic Studies: Utilized in university laboratories for advanced organic synthesis projects and the development of new synthetic methodologies.
• Preclinical Development: Supports early-stage drug development processes, including pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	4-(3,4-Dihydro-6,7-Dimethoxy-2(1H)-Isoquinolinyl)-n-[2-(3,4-Dimethoxyphenyl)Ethyl]-6,7-Dimethoxy-2-Quinazolinamine Monohydrochloride
CAS No.	142715-48-8
Molecular Formula	C₃₁H₃₆N₄O₆ • HCl
Molecular Weight	585.10 g/mol (Free base: 548.64 g/mol)
Synonyms	4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine hydrochloride; 4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine monohydrochloride; Quinazolinamine derivative hydrochloride; TAK-147 analog (research compound); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents. We support compliance with cGMP guidelines where applicable for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.