Description

(R)-(+)-4-tert-Butyl-2-Oxazolidinone CAS NO 142618-93-7 is a high-purity, enantiomerically pure chiral auxiliary and building block of significant importance in asymmetric synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, which is critical for developing pharmaceuticals and fine chemicals with high optical purity. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality chiral reagents.

Application

• As a chiral auxiliary in Evans aldol reactions and related asymmetric carbon-carbon bond-forming processes.
• Building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and intermediates.
• Use in the preparation of chiral catalysts and ligands for homogeneous catalysis.
• Key starting material in the research and development of novel agrochemicals and specialty chemicals.
• Tool compound in academic and industrial research for studying stereochemistry and reaction mechanisms.
• Intermediate in the synthesis of complex natural products and bioactive molecules.

Basic Information

Product Name	(R)-(+)-4-tert-Butyl-2-Oxazolidinone
CAS No.	142618-93-7
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-4-tert-Butyl-2-oxazolidinone; (R)-(+)-4-(1,1-Dimethylethyl)-2-oxazolidinone; (R)-4-(tert-Butyl)-1,3-oxazolidin-2-one; (R)-tert-Butyl Oxazolidinone; Evans Auxiliary (R)-tert-Butyl variant; (R)-4-tert-Butyl-2-oxazolidinone; (R)-N-tert-Butyl Oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-tert-Butyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.