Description

Calanolide E is a naturally occurring coumarin derivative, a class of compounds known for their significant biological activity. This specific compound is of high interest for its role as a key intermediate in the synthesis of more complex bioactive molecules and for research into novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing new drug candidates and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex Calanolide analogs and other coumarin-based active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard or investigational compound in biochemical and pharmacological studies, particularly in virology and oncology research.
• Lead Compound Development: Acts as a structural scaffold for medicinal chemists to design and optimize new drug candidates with potential antiviral or anticancer properties.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create novel chemical entities for high-value applications in life sciences.
• Academic Studies: Utilized in university and institutional labs for teaching and research on natural product chemistry, isolation techniques, and bioactivity assays.

Basic Information

Product Name	Calanolide E
CAS No.	142566-61-8
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	(-)-Calanolide E; NSC 675447; (10R,11S,12S)-10,11-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H-benzo[1,2-b:3,4-b']dipyran-2-one; 2H,6H-Benzo[1,2-b:3,4-b']dipyran-2-one, 10,11-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-, (10R,11S,12S)-
EINECS	Contact for details

Quality Control

Our Calanolide E is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.