Description

3-Amino-6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique benzo[b]thiophene core and reactive amino and ester functionalities enable complex molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its fluorine-substituted aromatic system.
• Material Science Precursor: Serves as a monomer or precursor for advanced organic electronic materials, such as semiconductors or light-emitting materials.
• Dye and Pigment Synthesis: Employed in the creation of specialized dyes and pigments due to its chromophoric benzo[b]thiophene structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	3-Amino-6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	142363-99-3
Molecular Formula	C10H8FNO2S
Molecular Weight	225.24 g/mol
Synonyms	Methyl 3-Amino-6-fluorobenzo[b]thiophene-2-carboxylate; 6-Fluoro-3-aminobenzo[b]thiophene-2-carboxylic acid methyl ester; 3-Amino-6-fluoro-1-benzothiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-6-fluoro-3-aminobenzo[b]thiophene; 142363-99-3; 3-Amino-6-fluorobenzo[b]thiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.