Description

(7-Bromoheptyl)Carbamic Acid tert-Butyl Ester is a versatile bifunctional organic building block featuring both a protected amine and a terminal bromoalkyl chain. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily utilized by medicinal chemists and process development scientists for constructing molecular scaffolds, linker arms, and as a key intermediate in the preparation of active pharmaceutical ingredients (APIs) and functionalized polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the introduction of functionalized heptyl linkers in drug discovery programs, particularly for kinase inhibitors and targeted therapeutics.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a crucial component for constructing E3 ligase ligands and linker segments in bifunctional degrader molecules.
• Bioconjugation and Linker Chemistry: Used to attach payloads, fluorophores, or other functional groups to biomolecules (e.g., peptides, antibodies) via its reactive bromo and protected amine functionalities.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for creating functionalized polymers with specific amine-reactive sites post-deprotection.
• Chemical Biology Tool Development: Employed in the synthesis of activity-based probes and affinity labels to study enzyme function and protein interactions.
• Agrochemical Synthesis: An intermediate in the preparation of novel herbicides and plant growth regulators requiring specific alkyl chain modifications.

Basic Information

Product Name	(7-Bromoheptyl)Carbamic Acid tert-Butyl Ester
CAS No.	142356-34-1
Molecular Formula	C12H24BrNO2
Molecular Weight	294.23 g/mol
Synonyms	tert-Butyl N-(7-bromoheptyl)carbamate; N-(7-Bromoheptyl)carbamic Acid 1,1-Dimethylethyl Ester; Boc-7-Aminoheptyl Bromide; 7-Bromoheptylamine Boc derivative; N-Boc-7-bromoheptylamine; 1-Bromo-7-[(tert-butoxycarbonyl)amino]heptane; Boc-NH-(CH2)7-Br; (7-Bromo-1-heptyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of (7-Bromoheptyl)Carbamic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC), identity (NMR, IR), and impurity profile is supplied with each shipment to guarantee reproducible results and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.