Description

tert-Butyl 3-(2-Hydroxyethyl)-1H-Indole-1-Carboxylate is a protected indole derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a reactive scaffold where the indole nitrogen is protected by a Boc (tert-butoxycarbonyl) group and the side chain offers a primary alcohol for further functionalization. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for creating complex heterocyclic molecules and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate an indole core.
• Peptidomimetic Synthesis: Serves as a scaffold for creating non-peptide compounds that mimic the structure and function of peptides.
• Material Science: Potential monomer or intermediate for synthesizing specialty polymers and organic electronic materials.
• Academic & R&D: Employed in medicinal chemistry laboratories for structure-activity relationship (SAR) studies and library synthesis.
• Fluorescent Probe Development: The indole moiety can be utilized in the design of fluorescent markers and sensors for biological imaging.

Basic Information

Product Name	tert-Butyl 3-(2-Hydroxyethyl)-1H-Indole-1-Carboxylate
CAS No.	141972-32-9
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-(2-hydroxyethyl)-, 1,1-dimethylethyl ester; 1-Boc-3-(2-hydroxyethyl)indole; tert-Butyl 3-(2-hydroxyethyl)indole-1-carboxylate; 3-(2-Hydroxyethyl)-1H-indole-1-carboxylic acid tert-butyl ester; Boc-3-(2-Hydroxyethyl)indole; N-Boc-3-(2-hydroxyethyl)indole; 141972-32-9; tert-Butyl 3-(2-Hydroxyethyl)indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-Hydroxyethyl)-1H-Indole-1-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.