Description

(E)-3-(Pyridin-2-Ylmethylene)Indolin-2-One CAS NO 141946-34-1 is a high-purity organic compound belonging to the class of indolin-2-one derivatives, characterized by its distinct (E)-configured exocyclic double bond. This compound serves as a critical advanced intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted small-molecule drug candidates.
• Chemical Research: Serves as a versatile scaffold for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Organic Synthesis: Used in the preparation of more complex heterocyclic compounds and functional materials.
• Biochemical Research: Potential use as a probe or ligand in biochemical assays due to its specific molecular architecture.

Basic Information

Product Name	(E)-3-(Pyridin-2-Ylmethylene)Indolin-2-One
CAS No.	141946-34-1
Molecular Formula	C₁₄H₁₀N₂O
Molecular Weight	222.24 g/mol
Synonyms	(E)-3-(2-Pyridylmethylene)indolin-2-one; (E)-3-[(Pyridin-2-yl)methylene]indolin-2-one; 2H-Indol-2-one, 3-[(2-pyridinyl)methylene]-1,3-dihydro-, (3E)-; (E)-3-(Pyridin-2-ylmethylidene)-1,3-dihydro-2H-indol-2-one; (E)-3-(2-Pyridylmethylidene)oxindole; (E)-3-(2-Pyridinylmethylene)-1,3-dihydro-2H-indol-2-one; (E)-3-(Pyridin-2-ylmethylene)indolin-2-one; (E)-3-(2-Pyridinylmethylene)oxindole
EINECS	Contact for details

Quality Control

Our (E)-3-(Pyridin-2-Ylmethylene)Indolin-2-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and other relevant analytical techniques to verify identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.