Description

Diethyl Chlorophosphate-D10 is a deuterated organophosphorus compound where ten hydrogen atoms are replaced by deuterium, serving as a critical stable isotope-labeled standard. This high-purity compound is essential for applications requiring precise internal standards in quantitative mass spectrometry, eliminating interference from unlabeled analytes. It is primarily utilized by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental sectors for method development, metabolism studies, and trace-level quantification.

Application

• Internal Standard for LC-MS/MS analysis in pharmacokinetic and bioanalytical studies.
• Metabolite identification and quantification in drug metabolism and disposition (DMPK) research.
• Quantitative analysis of organophosphate pesticides, herbicides, or their degradation products in environmental samples.
• Stable isotope dilution method for the accurate determination of related chemical warfare agent degradation products.
• Chemical synthesis research as a deuterium-labeled building block or reagent.
• Quality control and method validation in pharmaceutical impurity profiling.
• Forensic analysis and toxicology for the definitive identification of specific organophosphorus compounds.

Basic Information

Product Name	Diethyl Chlorophosphate-D10
CAS No.	141870-47-5
Molecular Formula	C4D10ClO3P
Molecular Weight	203.58 g/mol (deuterated form)
Synonyms	Diethyl Phosphorochloridate-D10; Chlorophosphoric Acid Diethyl Ester-D10; Diethoxyphosphoryl Chloride-D10; DECP-D10; Phosphorochloridic Acid, Diethyl Ester-D10; (Diethoxyphosphoryl)chloride-D10; Diethyl Chloridophosphate-D10
EINECS	Contact for details

Quality Control

Our Diethyl Chlorophosphate-D10 is manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR (1H, 13C, 31P) and mass spectrometry to confirm deuterium incorporation and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and identity are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC or HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.